Residencias CABA Medicina Practice Questions - Buenos Aires City Health Residencies Contest (Concurso De Residencias Del Equipo De Salud Del GCABA - Medicina) Exam

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A 38-year-old female is evaluated for persistent grade 2 hypertension (blood pressure 168/102 mmHg) despite adherence to a three-drug regimen including enalapril, amlodipine, and hydrochlorothiazide. Routine laboratory testing reveals a serum potassium of 2.9 mEq/L (normal: 3.5-5.0 mEq/L) and a serum bicarbonate of 31 mEq/L. Which diagnostic screening test is the most appropriate next step to evaluate for the suspected secondary cause of her hypertension?
Correct Answer:
Morning plasma aldosterone concentration to plasma renin activity (PAC/PRA) ratio

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