Registered Respiratory Therapist CSE Practice Exam

Guillain-Barré syndrome classically presents with an abrupt, rapidly progressing weakness that begins in the legs and often ascends to involve other muscle groups, accompanied by reduced or absent reflexes. This motor-focused onset mirrors the peripheral nerve inflammation and demyelination that characterizes the condition, making acute leg weakness the hallmark seen early in evaluation. Sensory symptoms like tingling can occur, but the defining feature in the initial assessment is that sudden leg weakness with diminishing reflexes. The other symptoms don’t fit this pattern: a chronic cough points to airway or lung issues, seizures are not typical of a peripheral demyelinating process, and visual hallucinations suggest central nervous system or psychiatric causes rather than Guillain-Barré. Recognizing the acute, ascending motor weakness helps distinguish GBS from other conditions and prompts urgent assessment of respiratory function, since weakness can progress to involve the respiratory muscles.