RACP DWE Practice Questions - RACP Divisional Written Examination (Basic Training) Exam

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A 72-year-old woman with heart failure with reduced ejection fraction is already on an ACE inhibitor, beta-blocker and a mineralocorticoid receptor antagonist but remains symptomatic. Switching the ACE inhibitor to sacubitril/valsartan acts by which additional mechanism?

Inhibiting neprilysin to increase natriuretic peptide levels Blocking the funny current in the sinoatrial node Inhibiting sodium-glucose cotransporter 2 Blocking If channels and aldosterone simultaneously

Correct Answer:

Inhibiting neprilysin to increase natriuretic peptide levels

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