OPRA Exam Practice Questions - Overseas Pharmacist Readiness Assessment (OPRA) Exam

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A patient with type 1 diabetes presents with hyperglycaemia, ketonaemia, and metabolic acidosis. Which underlying mechanism best explains the ketone production?

Excess insulin driving glucose into cells Increased peripheral glucose uptake Suppression of glucagon secretion Absolute insulin deficiency increasing lipolysis and hepatic ketogenesis

Correct Answer:

Absolute insulin deficiency increasing lipolysis and hepatic ketogenesis

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