MTM Pediatric Obesity Practice Test

Which drug is NOT approved for weight management because it has low efficacy?

Orlistat Phentermine Liraglutide Lisdexamfetamine

Correct Answer:

Lisdexamfetamine

Explanation:

Medications for weight management are approved only when trials show meaningful, sustained weight loss with acceptable safety. Lisdexamfetamine hasn’t been approved for obesity because the weight loss it produces in studies isn’t substantial enough to meet regulatory standards, and it carries risks like potential misuse and cardiovascular effects. In contrast, orlistat, phentermine, and liraglutide have demonstrated clinically meaningful weight loss in obesity trials and have regulatory approval, though each has its own safety considerations.

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