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Internal Medicine Board Exam
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You are meeting a 20-year-old male who has complained for the previous two months about "puffy eyes" and "swollen ankles." Additionally, he says that his pee "sort of looks frothy and foamy." His vital signs during the examination are within normal ranges, and the funduscopy is uneventful save for minor bilateral edema 2+ in the bilateral feet to the ankle. He has never experienced any health issues or operations. His tests show an average serum creatinine level; a considerable 4-plus protein level without blood or bacteria is found in the urine. He has had a kidney biopsy, which on light microscopy appears normal but, on electron microscopy, reveals diffuse podocyte effacement. Negative immunofluorescence results. Which medical intervention is ideal for this patient?
Cyclophosphamide
Tacrolimus
Rituximab
Corticosteroids
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Correct Answer:
Corticosteroids
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