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INI CET Practice Questions - Institute Of National Importance Combined Entrance Test (INI CET) Exam

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A 45-year-old female presents with progressive dyspnoea, malar rash, and Raynaud phenomenon. Pulmonary function tests show restrictive pattern with reduced DLCO. Which antibody is most specific for diffuse cutaneous systemic sclerosis with rapidly progressive pulmonary fibrosis?
Correct Answer:
Anti-Scl-70 (anti-topoisomerase I) antibody

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