General Surgery Board Practice Questions - Saudi Board General Surgery Final Written Exam

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Six hours after receiving a transfusion of packed red blood cells, a 62-year-old female develops acute dyspnea, hypoxemia (SpO2 85%), and fever. Chest radiograph shows bilateral pulmonary infiltrates. Her pulmonary capillary wedge pressure (PCWP) is normal, and there are no signs of jugular venous distention or peripheral edema. Which of the following is the most likely diagnosis?
Correct Answer:
Transfusion-Related Acute Lung Injury (TRALI)

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