FVH Kleintiere Practice Questions - Fachtierarzt FVH Für Kleintiere (Switzerland) Exam

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A 13-year-old domestic shorthair cat is diagnosed with hyperthyroidism (total T4 = 110 nmol/L, reference 15-50 nmol/L) and normal pre-treatment serum creatinine (120 umol/L). Following 4 weeks of methimazole therapy, total T4 is 25 nmol/L, but serum creatinine increases to 240 umol/L. What is the primary mechanism underlying this biochemical change?

Methimazole-induced immune-complex glomerulonephritis with acute nephrotic syndrome Direct nephrotoxicity of antithyroid medications on the proximal convoluted tubular epithelium Acute renal infarction secondary to thyroid storm-induced systemic microthrombosis Resolution of thyrotoxic hyperfiltration reducing glomerular filtration rate (GFR) and unmasking underlying chronic kidney disease (CKD)

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Resolution of thyrotoxic hyperfiltration reducing glomerular filtration rate (GFR) and unmasking underlying chronic kidney disease (CKD)

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