Facharzt FMH Anästhesiologie Practice Questions - Facharzt FMH Für Anästhesiologie Spécialiste FMH En Anesthésiologie Specialista FMH In Anestesiologia Exam

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A 58-year-old male with severe ischemic cardiomyopathy (LVEF 22%) presents for urgent bowel obstruction repair. The anesthesiologist selects etomidate for induction of general anesthesia. What is the primary endocrine consideration associated with even a single induction dose of etomidate?

Immediate suppression of thyroid-stimulating hormone (TSH) secretion lasting 48 hours Reversible inhibition of 11-beta-hydroxylase, leading to transient adrenocortical suppression Profound stimulation of aldosterone synthase, causing acute hyperkalemia and metabolic acidosis Irreversible destruction of the adrenal cortex, requiring lifelong mineralocorticoid replacement

Correct Answer:

Reversible inhibition of 11-beta-hydroxylase, leading to transient adrenocortical suppression

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