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ESTER Reumatologia Practice Questions - Título De Especialista Em Reumatologia (Sociedade Brasileira De Reumatologia AMB) Exam

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A 52-year-old woman presents with severe Raynaud phenomenon, sclerodactyly limited to the fingers and hands distal to the metacarpophalangeal joints, multiple facial telangiectasias, and subcutaneous calcinosis on the finger pads. Capillaroscopy shows enlarged giant capillaries without severe avascular areas. Which autoantibody profile is most characteristically associated with this clinical phenotype and confers a higher risk of isolated pulmonary arterial hypertension (PAH)?
Correct Answer:
Anti-Centromere antibodies (ACA / CENP-B)

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