ESTER Reumatologia Practice Questions - Título De Especialista Em Reumatologia (Sociedade Brasileira De Reumatologia AMB) Exam

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An antinuclear antibody test performed by indirect immunofluorescence on HEp-2 cells demonstrates a fine speckled nuclear pattern designated as AC-4 by the International Consensus on ANA Patterns (ICAP). Which target autoantigen pair is most characteristically associated with this staining pattern?

Sm and U1-RNP spliceosomal proteins SSA/Ro and SSB/La ribonucleoproteins Topoisomerase I (Scl-70) and RNA Polymerase III Histidyl-tRNA synthetase (Jo-1) and SRP

Correct Answer:

SSA/Ro and SSB/La ribonucleoproteins

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