ESTER Reumatologia Practice Questions - Título De Especialista Em Reumatologia (Sociedade Brasileira De Reumatologia AMB) Exam

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A 26-year-old woman presents with polyarthralgias, malar erythema, and mild proteinuria (0.6 g/24h). Indirect immunofluorescence on HEp-2 cells reveals an antinuclear antibody (ANA / FAN) titer of 1:1280 with a homogeneous nuclear pattern (ICAP AC-1). In the International Consensus on ANA Patterns (ICAP), which autoantigens are primarily associated with the AC-1 homogeneous pattern?
Correct Answer:
Double-stranded DNA (dsDNA), histones, and nucleosomes

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