Disorders Of The Lens Practice Test

What type of LIU is due to capsule rupture?

Phacoclastic uveitis Phacolytic uveitis Iris bombe Chronic anterior uveitis

Correct Answer:

Phacoclastic uveitis

Explanation:

Phacoclastic uveitis occurs when the lens capsule ruptures, releasing the entire lens contents into the anterior chamber. That abrupt exposure of highly antigenic lens proteins triggers a robust inflammatory response in the uveal tissues, often presenting acutely after trauma or a rupture during surgery. This distinguishes it from phacolytic uveitis, which happens with an intact capsule in a hypermature lens where leaked soluble proteins slowly provoke inflammation. Iris bombe is not driven by lens protein leakage at all; it’s a pupillary block mechanism causing anterior chamber shallowing and iris bowing. Chronic anterior uveitis refers to long-standing inflammation of the anterior uveal tract, not specifically linked to capsule rupture.

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