Certified Diabetes Educator Practice Exam

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What is the role of amylin in fuel metabolism?
Correct Answer:
Inhibits glucagon secretion and regulates glucose in blood
Explanation:
Amylin plays a significant role in fuel metabolism by helping to regulate blood glucose levels and inhibiting the secretion of glucagon, a hormone that increases blood glucose. When food is consumed, amylin is secreted alongside insulin from the beta cells of the pancreas. One of its primary functions is to slow gastric emptying, which helps to moderate the rate at which glucose enters the bloodstream after meals. By inhibiting glucagon, amylin prevents the liver from producing and releasing excessive amounts of glucose into the bloodstream, thereby aiding in maintaining stable blood sugar levels. This regulatory effect is crucial, especially in individuals with diabetes, where glucose management is a primary concern. The other options do not align with the primary SAMPLEfunctions of amylin. While gastric emptying does occur, amylin's role is not to increase it, nor does it stimulate appetite or enhance glucose production in the liver. Instead, its actions are geared toward creating a more stable post-meal blood glucose environment.

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