CRNI - Certified Registered Nurse Infusion

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A patient receiving the immune checkpoint inhibitor pembrolizumab reports a new onset of profuse, watery diarrhea two weeks after their third infusion. The CRNI should recognize this as a potential sign of which common immune-related adverse event (irAE)?

Cytokine release syndrome. Immune-mediated colitis. A Type 1 hypersensitivity reaction. Drug-induced pancreatitis.

Correct Answer:

Immune-mediated colitis.

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