Certified Manager Of Animal Resources (CMAR) AR Practice Exam

Which of the following is an inbred strain of mice?

CD1 Swiss Webster ICR BALB/c

Correct Answer:

BALB/c

Explanation:

Inbred strains are created by long-term brother-sister matings to produce nearly identical genetics across individuals, giving researchers a uniform background to study. BALB/c is a classic example of an inbred strain, maintained for many generations to maintain genetic and phenotypic consistency that’s valuable for immunology and cancer research. The other strains listed are outbred stocks, kept to preserve genetic diversity and heterogeneity, which makes them less uniform for controlled experiments. That combination of consistent genetics and well-documented traits makes BALB/c the best choice.

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