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Cert Rheumatology(SA) Paed Practice Questions - Sub-specialty Certificate In Paediatric Rheumatology Of The College Of Paediatricians Of South Africa Exam

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A 6-year-old girl presents with a 3-week history of daily spiking fevers up to 39.8°C that return to baseline once daily, accompanied by a salmon-pink macular rash on her trunk that appears during fever spikes and fades as her temperature normalizes. Physical examination reveals generalized lymphadenopathy, hepatosplenomegaly, and bilateral wrist and ankle arthritis. Laboratory testing demonstrates WBC 24.5 x 10^9/L (85% neutrophils), platelets 650 x 10^9/L, ESR 95 mm/hr, CRP 140 mg/L, and serum ferritin 3,200 µg/L. ANA and RF are negative. What is the most likely diagnosis?
Correct Answer:
Systemic Juvenile Idiopathic Arthritis (sJIA)

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