CBC Título De Especialista Em Cirurgia Geral Practice Questions - Exame Para Obtenção Do Título De Especialista Em Cirurgia Geral - CBC AMB Exam

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During the initial neuroendocrine and metabolic response to major surgical trauma (resposta metabólica ao trauma cirúrgico - REMT), which of the following hormonal alterations is characteristically observed in the immediate post-injury 'ebb phase' transitioning into the 'flow phase'?

Increased secretion of ACTH, cortisol, catecholamines, and glucagon accompanied by peripheral insulin resistance and accelerated muscle proteolysis. Suppression of the hypothalamic-pituitary-adrenal axis with profound hypoinsulinemia and generalized stimulation of glycogen synthesis. Marked elevation of anabolic hormones including growth hormone and testosterone with sustained nitrogen retention. Selective hypersecretion of thyroid hormones (T3 and T4) without activation of the sympathoadrenal system.

Correct Answer:

Increased secretion of ACTH, cortisol, catecholamines, and glucagon accompanied by peripheral insulin resistance and accelerated muscle proteolysis.

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