Canadian Entry To Practice Pharmacy Technician Qualifying Examination (PEBC)

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A patient is taking warfarin and begins taking St. John's Wort for depression. What is the primary pharmacotherapy concern?

St. John's Wort increases warfarin levels, raising bleeding risk St. John's Wort is a CYP450 inducer that decreases warfarin levels, raising clot risk There is no significant interaction between these agents St. John's Wort causes warfarin to be excreted faster via the kidneys

Correct Answer:

St. John's Wort is a CYP450 inducer that decreases warfarin levels, raising clot risk

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