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A 62-year-old presents with right hemiparesis and aphasia, last known well 2 hours ago. Non-contrast CT shows no hemorrhage, no large established infarct. BP is 172/96 mmHg. Which dose of IV alteplase is correct?

0.9 mg/kg total (max 90 mg): 10% bolus, 90% over 60 minutes 0.6 mg/kg total: full dose as bolus 1.2 mg/kg total: infused over 30 minutes 0.25 mg/kg total: bolus only

Correct Answer:

0.9 mg/kg total (max 90 mg): 10% bolus, 90% over 60 minutes

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